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2023 OCR A LEVEL BIOLOGY B QUESTION PAPER 2 [H422/02: Scientific literacy in biology]
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2023 OCR A LEVEL BIOLOGY B QUESTION PAPER 2 [H422/02]
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2023 OCR A LEVEL BIOLOGY B QUESTION PAPER 2 [H422/02: Scientific literacy in biology] 


 


1 This question is based on the Advance Notice Article ‘Development of therapeutic antibodies 
for the treatment of disease’.
 (a) (i) State what is meant by the term antigen.
 ...........................................................................................................................................
 ...................................................................................................................................... [1]
 (ii) Scientists can combine antibody fragments using phage display to produce many 
different antibodies, each specific to a different antigen.
 Using the abbreviations from Fig. 1 in the Advance Notice Article, explain how 
combining antibody fragments allows scientists to produce many different antibodies, 
each specific to a different antigen.
 ...........................................................................................................................................
 ...........................................................................................................................................
 ...........................................................................................................................................
 ...........................................................................................................................................
 ...................................................................................................................................... [2]
 (iii) The B cell receptor is an IgG molecule with the same structure as the human IgG 
shown in Fig. 1 in the Advance Notice Article.
 Use an abbreviation from Fig. 1 to identify the part of the B cell receptor that will be 
attached to the cell surface membrane of a B cell.

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Author Future Focus
Published 30 Jul 2024
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2023 OCR A LEVEL A LEVEL BIOLOGY BIOLOGY B OCR A LEVEL BIOLOGY H422/02 BIOLOGY QUESTION PAPER 2 OCR BIOLOGY B
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